Year Ailment Place
1350 Bubonic plague WW*
1499 Bubonic plague UK London
1507 "Fever" UK* 1507-51
1551 Influenza UK
1555 Famine UK Rains brought famine & weakness
1556 Bubonic plague UK *1556-63 Extreme
1578 Bubonic plague UK
1586 Bubonic plague UK*Chesterfield. Harvest failed
1591 Acute distress UK
1593 Bubonic plague UK
1596 Famine UK* Harvests failed & epidemics
1603 Bubonic plague UK
1612 Bubonic plague UK
1617 Smallpox US *Native Indians
1623 Bad years UK 2 years
1625 Bubonic plague UK
1626 Bubonic plague UK
1630 Very bad year UK Many died
1631 Bubonic plague UK
1633 Smallpox US *Native Indians
1636 Bubonic plague UK
1637 Bubonic plague UK
1647 Yellow FeverWest Indies
1648 Smallpox US
1648 Whooping coughUS
1654 Bubonic plague UK
1657 Measles US Boston
1662 Smallpox US NY
1665 Bubonic plague UK Extreme
1666 Bubonic plague UK Eyam
1668 Yellow Fever US NY
1677 Smallpox US *Boston
1687 Measles US Boston
1690 Yellow Fever US NY
1699 Yellow Fever US SC
1702 Yellow Fever US *NY
1702 Scarlet Fever US Boston
1706 Yellow Fever US SC
1713 Measles US Boston
1721 Smallpox US Boston
1723 Influenza WW
1723 Famine UK *7 years poor harvests & epidemics
1728 Yellow Fever US SC
1729 Measles US Boston
1732 Yellow Fever US SC
1732 Influenza WW*
1735 Diphtheria/scarlet feverUS *4 yrs -New England
1738 Smallpox US S.Carolina
1739 Measles US *Boston
1743 Yellow Fever US *NY
1747 Measles US CT, NY, PA, SC
1759 Measles US North America
1761 Influenza US& West Indies
1763 Smallpox US*Boston
1772 Measles US
1775 Influenza WW*
1783 Bilious disorder US Fatal
1788 Measles US PA, NY
1789 Influenza US
1792 Yellow Fever US *7 yrs
1793 Unknown US PA
1793 Influenza US Vermont, Virginia
1802 Smallpox US Nebraska
1803 Yellow Fever US NY

1820 "Fever" US*
1826 Cholera WW *1826-37

1826 Dengue Fever US* and West Indies
1829 Malaria US*
1831 Cholera UK Started WW 1826
1831 Cholera US*
1832 Influenza US
1833 Cholera US Ohio

1834 Cholera US NY
1837 Typhus US PA
1837 Smallpox US Indians
1841 Yellow Fever US
1847 Measles US Indians
1847 Yellow Fever US NO
1847 Influenza WW*
1848 Cholera WW*
1850 Yellow Fever US
1850 Influenza US*
1850 Dengue Fever US*
1851 Cholera US IL
1852 Yellow Fever US NO
1853 Cholera Birmingham?This came from a UK report with the ?
1855 Yellow Fever US
1857 Influenza WW*
1860 Smallpox US* Pennsylvania
1861 Epidemics US* Civil war numerous infectious diseases
1865 Smallpox US*
1865 Cholera US
1865 Typhus US*
1868 Smallpox US* 7 yrs
1873 Influenza UK* N. America & Europe
1873 Cholera US
1878 Yellow Fever US NO

1885 Typhoid US PA
1886 Yellow Fever US FL
1889 Influenza WW*
1893 Polio US 1st known outbreak
1900 Plague US*
1901 Smallpox US*
1907 Polio US *9 yrs.
1917 Influenza WW* Worst ever
1931 Polio US
1942 Polio US 11 yrs

* - means the epidemic is spread over more than one year.